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Comparative Co-Evolution Analysis Between the HA and NA Genes of Influenza A Virus

1 Jan 2018

Abstract excerpt

Influenza A virus subtypes are determined based on envelope proteins encoded by the hemagglutinin (HA) gene and the neuraminidase (NA) gene, which are involved in attachment to the host, pathogenicity, and progeny production. Here, we evaluated such differences through co-evolution analysis between the HA and NA genes based on subtype and host. Event-based cophylogeny analysis revealed that humans had higher...

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PMID: 30038490
DOI: 10.1177/1178122x18788328

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