Article
Paraoxonase gene cluster is a genetic marker for early microvascular complications in type 1 diabetes.
Diabetic medicine : a journal of the British Diabetic Association - 1 Mar 2002
Kao Y, Donaghue K C, Chan A, Bennetts B H, Knight J, Silink M
Abstract excerpt
BACKGROUND: Paraoxonase is a serum enzyme, which prevents oxidation of low-density lipoprotein (LDL) by hydrolyzing lipid peroxides. Two polymorphisms in PON1 gene have been associated with cardiovascular and microvascular diseases in both diabetic and non-diabetic patients. AIMS: The current project was designed to investigate the association between the polymorphisms of two PON genes and diabetes microvascular...
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