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Article

HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter.

The Journal of biological chemistry - 31 May 2002

Yang Yili, Dong Bei, Mittelstadt Paul R, Xiao Hua, Ashwell Jonathan D

Abstract excerpt

HIV Tat can enhance activation-induced up-regulation of Fas ligand (FasL), which may contribute to T cell apoptosis in human immune deficiency virus (HIV)-infected individuals. We have assessed functional and physical interactions between Tat and the Egr family of transcription factors (Egr-1, -2...

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Identifiers

PMID: 11909874
DOI: 10.1074/jbc.M201687200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11909874-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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