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Article

Sustained High Frequencies of Specific CD4 T Cells Restricted to a Single Persistent Virus

15 Apr 2002

Abstract excerpt

Replication of cytomegalovirus (CMV) is largely controlled by the cellular arm of the immune response. In this study the CMV-specific CD4 T-cell response was characterized in a cohort of apparently healthy individuals. In 11% of all individuals, extremely high frequencies, between 10 and 40%, were found. High-level frequencies of CMV-specific CD4 T cells persisted over several months and were not the result of an...

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PMID: 11907214
DOI: 10.1128/jvi.76.8.3748-3755.2002

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