Article
[Mutation and recombination variability of vaccine polioviruses isolated in Belarus (1960-1999)].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 2002
Beletskaia T S, Samoĭlovich E O, Korotkova E A, Scheslenok E P, Fel'dman E V
Abstract excerpt
One hundred and eight vaccine-derived strains of types 1, 2, and 3 poliovirus (25 PV1, 34 PV2, and 48 PV3) isolated in Belarus in 1960-1999 were analyzed by double restriction fragment length polymorphism assay (RFLP-1, -3D1). Forty-four (40.7%) of strains were genetically modified. Eight (7.4%) PV were modified by mutation, 16 (14.8%) by recombination, and 20 (18.5%) by both mutation and recombination. The...
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