Article
Residence at the expression site is necessary and sufficient for the transcription of surface antigen genes of Pneumocystis carinii.
Molecular microbiology - 1 Jul 1997
Sunkin S M, Stringer J R
Abstract excerpt
The major surface glycoprotein (MSG) of P. carinii f. sp. carinii is a family of proteins encoded by a family of heterogeneous genes. Messenger RNAs encoding different MSG isoforms start with the same sequence, called the upstream conserved sequence (UCS), which is encoded by a single locus. The mechanism by which the UCS becomes part of different MSG mRNAs is not obvious because at least 15 loci, which are...
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