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Article

Human dermal fibroblasts escape from the long-term phenocopy of senescence induced by psoralen photoactivation.

Experimental cell research - 1 Apr 2002

Ma Wenjian, Wlaschek Meinhard, Brenneisen Peter, Schneider Lars Alexander, Hommel Christina, Hellweg Christine, Sauer Heinrich, Wartenberg Maria, Herrmann Gernot, Meewes Christian, Boukamp Petra, Scharffetter-Kochanek Karin

Abstract excerpt

We have previously shown that following psoralen photoactivation (PUVA treatment) human dermal fibroblasts undergo long-term growth arrest as well as morphological and functional changes reminiscent of cellular senescence [ 1 ]. In the absence of molecular data on what constitutes normal senescence, it has been difficult to decide whether these PUVA-induced changes reflect cellular senescence or rather a mimic...

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PMID: 11900490
DOI: 10.1006/excr.2002.5476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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