Article
Clinical significance of poor CD3 response in head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2002
Shibuya Terry Y, Nugyen Nghia, McLaren Christine E, Li Kuo-Tung, Wei Wei-Zen, Kim Sanghun, Yoo George H, Rogowski Amy, Ensley John, Sakr Wael
Abstract excerpt
PURPOSE: The objective of our investigation was to prospectively study what the implications of an unresponsive CD3 receptor are on clinical outcome in advanced-stage head and neck cancer patients. EXPERIMENTAL DESIGN: Lymph node mononuclear cells were purified from cancer patients and stimulated with immobilized anti-CD3 in vitro for 8 days. Two populations were identified, nonresponders (NRs) with...
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