Article
Gene-environment interaction effects on behavioral variation and risk of complex disorders: the example of alcoholism and other psychiatric disorders.
Twin research : the official journal of the International Society for Twin Studies - 1 Feb 2002
Heath Andrew C, Todorov Alexandre A, Nelson Elliot C, Madden Pamela A F, Bucholz Kathleen K, Martin Nicholas G
Abstract excerpt
There have been few replicated examples of genotype x environment interaction effects on behavioral variation or risk of psychiatric disorder. We review some of the factors that have made detection of genotype x environment interaction effects difficult, and show how genotype x shared environment interaction (GxSE) effects are commonly confounded with genetic parameters in data from twin pairs reared together....
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