Article
Human immunodeficiency virus type 1 group m protease in cameroon: genetic diversity and protease inhibitor mutational features.
Journal of clinical microbiology - 1 Mar 2002
Fonjungo Peter N, Mpoudi Eitel N, Torimiro Judith N, Alemnji George A, Eno Laura T, Lyonga Esther J, Nkengasong John N, Lal Renu B, Rayfield Mark, Kalish Marcia L, Folks Thomas M, Pieniazek Danuta
Abstract excerpt
To establish a baseline for monitoring resistance to protease inhibitors (PIs) and examining the efficacy of their use among persons in Cameroon infected with human immunodeficiency virus type 1 (HIV-1), we analyzed genetic variability and PI resistance-associated substitutions in PCR-amplified protease (PR) sequences in strains isolated from 110 HIV-1-infected, drug-naïve Cameroonians. Of the 110 strains, 85...
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