Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Rab GTPase Ypt1p and tethering factors couple protein sorting at the ER to vesicle targeting to the Golgi apparatus.

Developmental cell - 1 Mar 2002

Morsomme Pierre, Riezman Howard

Abstract excerpt

GPI-anchored proteins exit the ER in distinct vesicles from other secretory proteins, and this sorting event can be reproduced in vitro. When extracts from a uso1 mutant were used, the sorting of GPI-anchored proteins from other secretory proteins was defective. Complementation with purified Uso1p restored sorting. The Rab GTPase Ypt1p and the tethering factors Sec34p and Sec35p, but not Bet3p, a member of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Vesicular Transport
Share to Amino Acid Transport Systems

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoplasmic Vesicles

Share to Glycosylphosphatidylinositols

Share to Golgi Apparatus

Share to Membrane Fusion

Share to rab GTP-Binding Proteins

Share to ras GTPase-Activating Proteins

Source

Identifiers

PMID: 11879636
DOI: 10.1016/s1534-5807(02)00133-8

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Rab GTPase Ypt1p and tethering factors couple protein sorting at the ER to vesicle targeting to the Golgi apparatus.PMID 11879636Read ↗

The ER v-SNAREs are required for GPI-anchored protein sorting from other secretory proteins upon exit from the ER.Semantic proximity Read ↗

The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis.Semantic proximity Read ↗

TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport.Semantic proximity Read ↗

A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum.Semantic proximity Read ↗

Assembly of the ER to Golgi SNARE complex requires Uso1p.Semantic proximity Read ↗

The TRAPP complex is a nucleotide exchanger for Ypt1 and Ypt31/32.Semantic proximity Read ↗

An essential role for a phospholipid transfer protein in yeast Golgi function.Semantic proximity Read ↗

The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic.Semantic proximity Read ↗

Establishing a role for the GTPase Ypt1p at the late Golgi.Semantic proximity Read ↗

Dependence of Ypt1 and Sec4 membrane attachment on Bet2.Semantic proximity Read ↗

Sec34p, a protein required for vesicle tethering to the yeast Golgi apparatus, is in a complex with Sec35p.Semantic proximity Read ↗

Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.