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Article

Stimulation of IRF-7 Gene Expression by Tumor Necrosis Factor α

1 May 2002

Abstract excerpt

Interferon regulatory factor 7 (IRF-7) plays an important role in innate immunity, where, together with IRF-3, it controls the expression of interferon A/B genes as well as chemokine RANTES (regulated on activation normal T cell expressed and secreted). Previously, we characterized human IRF-7 promoter and showed that an interferon-stimulated response element site in the first intron binds interferon-stimulated...

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PMID: 11877397
DOI: 10.1074/jbc.m111440200

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