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Article

UV-A induces persistent genomic instability in human keratinocytes through an oxidative stress mechanism.

Free radical biology & medicine - 1 Mar 2002

Phillipson Ross P, Tobi Simon E, Morris James A, McMillan Trevor J

Abstract excerpt

Ultraviolet-A (UV-A, 320 to 400 nm) radiation comprises 95% of the solar ultraviolet radiation (UVR) reaching the earth's surface. It has been associated experimentally and epidemiologically with malignant melanoma. In this study we investigated whether UV-A radiation can induce a persistent, heritable hypermutability in mammalian cells similar to that observed following ionising radiation (IR). Using the...

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Identifiers

PMID: 11864787
DOI: 10.1016/s0891-5849(01)00829-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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