Article
Protein oxidation, UVA and human DNA repair.
DNA repair - 1 Aug 2016
Karran Peter, Brem Reto
Abstract excerpt
Solar UVB is carcinogenic. Nucleotide excision repair (NER) counteracts the carcinogenicity of UVB by excising potentially mutagenic UVB-induced DNA lesions. Despite this capacity for DNA repair, non-melanoma skin cancers and apparently normal sun-exposed skin contain huge numbers of mutations that are mostly attributable to unrepaired UVB-induced DNA lesions. UVA is about 20-times more abundant than UVB in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
