Article
Chemiluminescence of superoxide generated by Candida albicans: differential effects of the superoxide generator paraquat on a wild-type strain and a respiratory mutant.
Medical mycology - 1 Feb 2002
Aoki S, Ito-Kuwa S, Nakamura K, Nakamura Y, Vidotto V, Takeo K
Abstract excerpt
We previously reported that a respiration-competent parent strain (K) of Candida albicans was more susceptible to the intracellular superoxide radical (O2-) generator paraquat (PQ) than was a respiration-deficient mutant (KRD-19), although both showed a similar sensitivity to extracellularly generated O2-. To clarify the cause of the differential PQ lethality, we developed a chemiluminescence method for measuring...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.