Article
T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region.
Genes and immunity - 1 Feb 2002
Wang Z C, Yunis E J, De los Santos M J, Xiao L, Anderson D J, Hill J A
Abstract excerpt
Recurrent pregnancy loss (RPL) is a common disorder during early gestation. Recent evidence suggests that T helper 1 (Th1)-type immunity is associated with unsuccessful pregnancy especially in women with RPL of otherwise unknown etiology, while Th2-type immunity is associated with pregnancy succe...
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