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Transcription of Human ABO Histo-blood Group Genes Is Dependent upon Binding of Transcription Factor CBF/NF-Y to Minisatellite Sequence

1 Oct 1997

Abstract excerpt

We have studied the transcriptional regulatory mechanism of the human histo-blood group ABO genes, and identified DNA cis-elements and trans-activating protein that control the expression of these genes which are important in blood transfusion and organ transplantation. We introduced the 5'-upstream sequence of ABO genes into the promoterless reporter vector and characterized the promoter activity of deletion...

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PMID: 9325321
DOI: 10.1074/jbc.272.41.25890

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