Sensitivity of rat testes to inhibitors of nucleic acid synthesis. III. The inheritance of mitomycin C-induced structural rearrangements of chromosomes.

Abstract excerpt

The inheritance of mitomycin C-induced aberrations was studied. Examination of spermatogonia showed statistically significant differences between the progeny of the untreated and treated rats in terms of total aberrant cells and chromosomal structural rearrangements. With the exception of gaps, breaks and fragments, which showed no significant differences between the progeny of the two treatment groups, the rest...

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