Article
[Cytogenetic effects of 1,4-dihydropyridine in various test systems].
TSitologiia i genetika - 1 Jan 2000
Kuzhir T D, Goncharova R I, Zolotareva G N
Abstract excerpt
Cytogenetic effect of 1,4-dihydropyridine was studied in different test-systems. The preparation is shown to decrease the level of complete sex-chromosome losses in Drosophila and chromosome aberration frequency in Allium fistulosum seedlings. The preparation does not affect spontaneous mutability of bone marrow cells in mice, high doses of the preparation have no mutagenic potential. Thus, 1,4-dihydropyridine...
Topics
- Animals
- Bone Marrow
- Chromosome Aberrations
- Dihydropyridines
- Dose-Response Relationship, Drug
- Drosophila
- Female
- Gamma Rays
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
