Article
Complex regulation of the human gene for the Z-DNA binding protein DLM-1.
Nucleic acids research - 15 Feb 2002
Rothenburg Stefan, Schwartz Thomas, Koch-Nolte Friedrich, Haag Friedrich
Abstract excerpt
Dlm-1 is a recently described gene which is upregulated in murine stromal cells lining tumors. The function of the 40 kDa DLM-1 protein is poorly understood. DLM-1 contains an N-terminal Z-DNA binding domain homologous to the Zalpha domain in the RNA editing enzyme ADAR1. We report the cloning of human and rat DLM-1. In addition to the Zalpha domain, three further conserved regions were identified. One of these...
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