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Article

Complete inhibition of tobamovirus multiplication by simultaneous mutations in two homologous host genes.

Journal of virology - 1 Mar 2002

Yamanaka Takuya, Imai Takahiro, Satoh Rena, Kawashima Arata, Takahashi Miki, Tomita Kayo, Kubota Kenji, Meshi Tetsuo, Naito Satoshi, Ishikawa Masayuki

Abstract excerpt

The TOM1 gene of Arabidopsis thaliana encodes a putative multipass transmembrane protein which is necessary for the efficient multiplication of tobamoviruses. We have previously shown that mutations severely destructive to the TOM1 gene reduce tobamovirus multiplication to low levels but do not impair it completely. In this report, we subjected one of the tom1 mutants (tom1-1) to another round of mutagenesis and...

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Source

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Identifiers

PMID: 11836427
DOI: 10.1128/jvi.76.5.2491-2497.2002
PMCID: PMC135938

Genes

TOM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Complete inhibition of tobamovirus multiplication by simultaneous mutations in two homologous host genes.PMID 11836427Read ↗

Arabidopsis TOBAMOVIRUS MULTIPLICATION (TOM) 2 locus encodes a transmembrane protein that interacts with TOM1.Semantic proximity Read ↗

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