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Neurotropins and Their Receptors Are Expressed in the Human Fetal Ovary

1 Feb 2002

Abstract excerpt

Mammalian ovarian development is characterized by a sequential pattern of mitotic proliferation of oogonia, initiation then arrest of meiosis, and primordial follicle formation. The factors regulating these processes are poorly understood. The neurotropins are survival and differentiation factors in the nervous system, acting via high affinity receptors of the trk protooncogene family and the low affinity p75...

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PMID: 11836338
DOI: 10.1210/jcem.87.2.8221

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