Patterns of low-affinity immunoglobulin receptor polymorphisms in stroke and homozygous sickle cell disease.

Abstract excerpt

Symptomatic stroke is a major complication of homozygous sickle cell (SS) disease, with a prevalence of approximately 10%. An elevated peripheral leukocyte count has been identified as a risk factor for hemorrhagic stroke in adults with SS disease. It has been observed that sickle cells coated with immunoglobulin have increased adherence to endothelial cells or phagocytes, possibly via binding to the low-affinity...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adolescent
• Share to Alleles