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Article

Two large British kindreds with familial Parkinson's disease: a clinico-pathological and genetic study.

Brain : a journal of neurology - 1 Jan 2002

Nicholl D J, Vaughan J R, Khan N L, Ho S L, Aldous D E W, Lincoln S, Farrer M, Gayton J D, Davis M B, Piccini P, Daniel S E, Lennox G G, Brooks D J, Williams A C, Wood N W

Abstract excerpt

We present the findings of a study of two large unrelated kindreds with autosomal dominant Parkinson's disease. The affected members were assessed clinically and with [(18)F]6-fluorodopa-PET and were indistinguishable from patients with the sporadic form of Parkinson's disease. In one kindred, an affected member was examined subsequently at autopsy and Lewy bodies were present in a distribution typical of...

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Identifiers

PMID: 11834592
DOI: 10.1093/brain/awf013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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