[Genes of micrometastasis in bone marrow of patients with colorectal cancer].

Abstract excerpt

OBJECTIVE: To detect the gene of micrometastasis in bone marrow of patients with colorectal cancer. METHODS: PCR-SSCP/silver stain technique was used to find out the metastatic cancer cells in 51 bone marrow samples in different time. RESULTS: The total positive rate of mutations of p53 and K-ras in bone marrow was 37.25% before operation. The incidence of mutations was obviously correlated with Duke's stage and...

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