Article
Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections.
Development (Cambridge, England) - 1 Feb 2002
Marín Oscar, Baker Joshua, Puelles Luis, Rubenstein John L R
Abstract excerpt
We have investigated the mechanisms that control the guidance of corticofugal projections as they extend along different subdivisions of the forebrain. To this aim, we analyzed the development of cortical projections in mice that lack Nkx2-1, a homeobox gene whose expression is restricted to two domains within the forebrain: the basal telencephalon and the hypothalamus. Molecular respecification of the basal...
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