Article
Genotypic resistance profile in treatment-experienced HIV-infected individuals after abacavir and efavirenz salvage regimen.
Antiviral research - 1 Feb 2004
Vallejo Alejandro, Olivera Mercedes, Rubio Amalia, Sánchez-Quijano Armando, Lissen Eduardo, Leal Manuel
Abstract excerpt
Once highly active antiretroviral therapy (HAART) fails to suppress HIV replication and resistant viruses emerge, it is difficult to find a salvage regimen since cross-resistance is high among the available classes of antiretroviral drugs. In this retrospective analysis, genotypic resistance profiles were analysed in 24 patients who switched treatment to abacavir (ABV), efavirenz (EFV), and either a NRTI or a PI...
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