Article
Cloning and characterization of opticin cDNA: evaluation as a candidate for canine oculo-skeletal dysplasia.
Gene - 9 Jan 2002
Pellegrini Beth, Acland Gregory M, Ray Jharna
Abstract excerpt
Opticin, a novel member of the leucine-rich repeat (LRR) family, has been reported to bind to collagen fibrils. Many members of the LRR family of extracellular matrix proteins have been reported to bind to fibrillar collagen and regulate the diameter of collagen fibrils and lateral fusion between fibrils. Collagen fibrils are important for the maintenance of the vitreous body in the eye and growth plate cartilage...
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