Article
Evaluation of candidate genes as a cause of chondrodysplasia in Labrador retrievers.
Veterinary journal (London, England : 1997) - 1 Feb 2011
Smit Jelke Jan, Temwitchitr Jedee, Brocks Bouvien A W, Nikkels Peter G J, Hazewinkel Herman A W, Leegwater Peter A J
Abstract excerpt
Chondrodysplasia (CD) is a disabling, hereditary disease in Labradors with short limbs, warranting genetic screening in families at risk. Segregation analysis of eight litters with 13 affected dogs showed that autosomal recessive inheritance was consistent with the observed incidence of CD in the litters. Possible involvement of eight candidate collagen genes (COL9A1, COL9A2, COL9A3, COMP, MATN3, COL2A1, COL11A1...
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