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Article

A polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma.

American journal of human genetics - 1 Mar 2002

Niimi Tomoaki, Munakata Mitsuru, Keck-Waggoner Catherine L, Popescu Nicholas C, Levitt Roy C, Hisada Michie, Kimura Shioko

Abstract excerpt

Several traits associated with asthma phenotypes, such as high total serum immunoglobulin E and bronchial hyperresponsiveness, have been linked by numerous genome-screen studies and linkage analyses to markers on human chromosome 5q31-q34. In the present article, we describe UGRP1 (encoding uteroglobin-related protein 1) as one of asthma-susceptibility genes that is located on chromosome 5q31-q32. UGRP1 is a...

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Identifiers

PMID: 11813133
DOI: 10.1086/339272
PMCID: PMC384948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma.PMID 11813133Read ↗

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UGRP1, a Uteroglobin/Clara Cell Secretory Protein-Related Protein, Is a Novel Lung-Enriched Downstream Target Gene for the T/EBP/NKX2.1 Homeodomain Transcription FactorSemantic proximity Read ↗

The -112G>A polymorphism of the secretoglobin 3A2 (SCGB3A2) gene encoding uteroglobin-related protein 1 (UGRP1) increases risk for the development of Graves' disease in subsets of patients with elevated levels of immunoglobulin E.Semantic proximity Read ↗

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