Article
Plasma UGRP1 levels associate with promoter G-112A polymorphism and the severity of asthma.
Allergology international : official journal of the Japanese Society of Allergology - 1 Mar 2008
Inoue Keiichi, Wang Xintao, Saito Junpei, Tanino Yoshinori, Ishida Takashi, Iwaki Daisuke, Fujita Teizo, Kimura Shioko, Munakata Mitsuru
Abstract excerpt
BACKGROUND: Uteroglobin-related protein 1 (UGRP1) is a secretory protein expressed in the airways and is speculated to have anti-inflammatory activity. In the mouse, its gene expression is down-regulated by interleukin (IL)-5 and -9, and up-regulated by IL-10. However, the precise role of UGRP1 in human inflammatory airway diseases such as asthma has not been clarified. The objectives of this study were to...
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