Article
Distribution of substitution rates and location of insertion sites in the tertiary structure of ribosomal RNA.
Nucleic acids research - 15 Dec 2001
Wuyts J, Van de Peer Y, De Wachter R
Abstract excerpt
The relative substitution rate of each nucleotide site in bacterial small subunit rRNA, large subunit rRNA and 5S rRNA was calculated from sequence alignments for each molecule. Two-dimensional and three-dimensional variability maps of the rRNAs were obtained by plotting the substitution rates on secondary structure models and on the tertiary structure of the rRNAs available from X-ray diffraction results. This...
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