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Article

Application of robust pedigree analysis in studies of complex genotype-phenotype relationships in fragile X syndrome.

American journal of medical genetics - 15 Jan 2002

Loesch D Z, Huggins R M, Taylor A K

Abstract excerpt

Relationships between the fragile X dynamic mutation and palmar and finger epidermal ridge measures were assessed using a robust modification of the maximum likelihood estimators for pedigree data. A total of 34 extended families affected with fragile X syndrome were used. Phenotypic traits included ridge count on the thumb and ridge breadth measured in the second palmar interdigital area bilaterally. Genotypic...

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Source

Identifiers

PMID: 11807888
DOI: 10.1002/ajmg.10129

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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