Article
Fixed and random effects in the variation of the finger ridge count: a study of fragile-X families.
American journal of human genetics - 1 May 1992
Loesch D Z, Huggins R M
Abstract excerpt
A maximum-likelihood scoring technique for analysis of pedigree data allows for the concurrent estimation of random and of fixed effects in a quantitative trait. We included both types of effects in genetic models, to study the sources of variation in finger ridge count in 54 large families affected with the fragile-X disorder. The fixed effects were represented by fragile X and sex, and the random effects by...
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