Article
Dopamine system genes not linked to social phobia.
Psychiatric genetics - 1 Dec 2001
Kennedy J L, Neves-Pereira M, King N, Lizak M V, Basile V S, Chartier M J, Stein M B
Abstract excerpt
Social phobia, particularly in its generalized form, has a genetic component in its etiology as suggested by positive twin studies and child temperament studies of social anxiety. Observations from functional imaging research suggest that dopamine function may be abnormal in the brains of patients with social phobia. Our investigation examined polymorphisms in the dopamine D2, D3 and D4 receptor genes, plus the...
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