Article
Surfactant gene polymorphisms and interstitial lung diseases.
Respiratory research - 1 Jan 2002
Pantelidis Panagiotis, Veeraraghavan Srihari, du Bois Roland M
Abstract excerpt
Pulmonary surfactant is a complex mixture of phospholipids and proteins, which is present in the alveolar lining fluid and is essential for normal lung function. Alterations in surfactant composition have been reported in several interstitial lung diseases (ILDs). Furthermore, a mutation in the surfactant protein C gene that results in complete absence of the protein has been shown to be associated with familial...
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