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Article

Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasome.

Proceedings of the National Academy of Sciences of the United States of America - 22 Jan 2002

Funakoshi Minoru, Sasaki Toru, Nishimoto Takeharu, Kobayashi Hideki

Abstract excerpt

Dsk2p from Saccharomyces cerevisiae belongs to the class of proteins that contain a ubiquitin-like (UbL) domain at the N terminus together with a ubiquitin-associated (UBA) domain at the C terminus. We show here that the C-terminal UBA domain of Dsk2p binds to K48-linked polyubiquitin chains, and the N-terminal UbL domain of Dsk2p interacts with the proteasome. Overexpression of Dsk2p caused the accumulation of...

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Identifiers

PMID: 11805328
DOI: 10.1073/pnas.012585199
PMCID: PMC117376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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