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Article

Mapping the Transcription and Replication Promoters of Respiratory Syncytial Virus

15 Feb 2002

Abstract excerpt

An important, unresolved issue in mononegavirus biology is whether or not transcription is initiated by the same promoter as RNA replication. In this study, residues important for respiratory syncytial virus (RSV) transcription and RNA replication were identified by subjecting the first 26 nucleotides of genome RNA to saturation mutagenesis. This analysis was performed using a genome analog that allowed...

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PMID: 11799161
DOI: 10.1128/jvi.76.4.1663-1672.2002

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