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Article

Hemodynamics and the Focal Origin of Atherosclerosis

1 Dec 2001

Abstract excerpt

Atherosclerosis originates at predictable focal and regional sites that are associated with complex flow disturbances and flow separations in large arteries. The spatial relationships associated with hemodynamic shear stress forces acting on the endothelial monolayer are considered in experiments that model regions susceptible to atherosclerosis (flow disturbance) and resistant to atherosclerosis (undisturbed...

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PMID: 11795312
DOI: 10.1111/j.1749-6632.2001.tb03925.x

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