Article
Directionality and processivity of molecular motors.
Current opinion in cell biology - 1 Feb 2002
Higuchi Hideo, Endow Sharyn A
Abstract excerpt
Analysis of a mutant with altered directionality has led to new insights into motor directionality. The prediction from current models for processivity of a two-heads-bound state has been confirmed by electron microscopy for myosin V and by unbinding experiments for kinesin. Evidence is emerging that non-processive motors bind their filament with one head, hydrolyze ATP and then release, requiring binding by a...
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