Article
Molecular dynamics studies of trinucleotide repeat DNA involved in neurodegenerative disorders.
Journal of biomolecular structure & dynamics - 1 Dec 2001
Jithesh P V, Singh P, Joshi R
Abstract excerpt
Expansion of trinucleotide repeat DNA of the classes CAG-CTG, CGG-CCG and GAA-TTC are found to be associated with several neurodegenerative disorders. Different mechanisms have been attributed to the expansion of triplets, mainly involving the formation of alternate secondary structures by such r...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
