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Article

Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Nov 2007

Bulhões A C, Goldani H A S, Oliveira F S, Matte U S, Mazzuca R B, Silveira T R

Abstract excerpt

The C/T-13910 mutation is the major factor responsible for the persistence of the lactase-phlorizin hydrolase (LCT) gene expression. Mutation G/A-22018 appears to be only in co-segregation with C/T-13910. The objective of the present study was to assess the presence of these two mutations in Brazilian individuals with and without lactose malabsorption diagnosed by the hydrogen breath test (HBT). Ten milk-tolerant...

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Identifiers

PMID: 17934640
DOI: 10.1590/s0100-879x2007001100004

Genes

LCT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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