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Article

Resistin Gene Expression in Human Adipocytes Is Not Related to Insulin Resistance

1 Jan 2002

Abstract excerpt

OBJECTIVES: Obesity is an important risk factor for the development of insulin resistance and type 2 diabetes. Recently, a newly described circulating hormone resistin, which is expressed primarily in adipocytes, has been shown to antagonize insulin action in mice. Resistin, therefore, has been suggested to play a role in the pathogenesis of insulin resistance. RESEARCH METHODS AND PROCEDURES: We studied the...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 11786595
DOI: 10.1038/oby.2002.1

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Research trail→

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Resistin Gene Expression in Human Adipocytes Is Not Related to Insulin ResistancePMID 11786595Read ↗

Insulin resistance and type 2 diabetes are not related to resistin expression in human fat cells or skeletal muscle.Semantic proximity Read ↗

Human Resistin Gene: Molecular Scanning and Evaluation of Association with Insulin Sensitivity and Type 2 Diabetes in CaucasiansSemantic proximity Read ↗

Identification of an alternative splicing transcript for the resistin gene and distribution of its mRNA in human tissueSemantic proximity Read ↗

Resistin mitigates stemness and metabolic profile of human adipose-derived mesenchymal stem cells via insulin resistance.Semantic proximity Read ↗

Adiponectin but not resistin is associated with insulin resistance-related phenotypes in baboons.Semantic proximity Read ↗

Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects.Semantic proximity Read ↗

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians.Semantic proximity Read ↗

Expression Profiling Identifies Genes That Continue to Respond to Insulin in Adipocytes Made Insulin-resistant by Treatment with Tumor Necrosis Factor-αSemantic proximity Read ↗

Transgenic and recombinant resistin impair skeletal muscle glucose metabolism in the spontaneously hypertensive rat.Semantic proximity Read ↗

Absence of evidence for an association between resistin gene variants and insulin resistance in an Asian population with low and high blood pressure.Semantic proximity Read ↗

Human Resistin Gene, Obesity, and Type 2 DiabetesSemantic proximity Read ↗

Study of Resistin gene expression in peripheral blood mononuclear cell and its gene polymorphism in a small range population.Semantic proximity Read ↗

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