Article
Resistin mitigates stemness and metabolic profile of human adipose-derived mesenchymal stem cells via insulin resistance.
Cytokine - 1 Feb 2021
Rawal Komal, Purohit Kishan M, Patel Tushar P, Karont Neeta, Gupta Sarita
Abstract excerpt
During obesity adipose tissue abundantly secrete pro-inflammatory adipokines like Tumour Necrosis factor-alpha (TNFα), resistin, leptin, etc. but reduced anti-inflammatory adipokines like adiponectin, interleukin (IL)-10, and IL-4. In our recent clinical study, it was observed that both gene expressions and stored levels of resistin were elevated in adipose tissue of metabolically obese Indians. Resistin...
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