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Article

Removal of a single alpha-tubulin gene intron suppresses cell cycle arrest phenotypes of splicing factor mutations in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Feb 2002

Burns C Geoffrey, Ohi Ryoma, Mehta Sapna, O'Toole Eileen T, Winey Mark, Clark Tyson A, Sugnet Charles W, Ares Manuel, Gould Kathleen L

Abstract excerpt

Genetic and biochemical studies of Schizosaccharomyces pombe and Saccharomyces cerevisiae have identified gene products that play essential functions in both pre-mRNA splicing and cell cycle control. Among these are the conserved, Myb-related CDC5 (also known as Cef1p in S. cerevisiae) proteins. The mechanism by which loss of CDC5/Cef1p function causes both splicing and cell cycle defects has been unclear. Here...

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Identifiers

PMID: 11784857
DOI: 10.1128/MCB.22.3.801-815.2002
PMCID: PMC133559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Removal of a single alpha-tubulin gene intron suppresses cell cycle arrest phenotypes of splicing factor mutations in Saccharomyces cerevisiae.PMID 11784857Read ↗

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