A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene.

Abstract excerpt

Strains of Escherichia coli with mutations in the ubiE gene are not able to catalyze the carbon methylation reaction in the biosynthesis of ubiquinone (coenzyme Q) and menaquinone (vitamin K2), essential isoprenoid quinone components of the respiratory electron transport chain. This gene has been mapped to 86 min on the chromosome, a region where the nucleic acid sequence has recently been determined. To identify...

Topics

• Alleles
• Amino Acid Sequence
• Base Sequence
• Escherichia coli
• Escherichia coli Proteins
• Genes, Bacterial
• Hydroquinones
• Methyltransferases
• Molecular Sequence Data
• Mutation
• Open Reading Frames
• Point Mutation
• Sequence Alignment