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Article

Hoxb8 is required for normal grooming behavior in mice.

Neuron - 3 Jan 2002

Greer Joy M, Capecchi Mario R

Abstract excerpt

Repertoires of grooming behaviors critical to survival are exhibited by most animal species, including humans. Genes that influence this complex behavior are unknown. We report that mice with disruptions of Hoxb8 show, with 100% penetrance, excessive grooming leading to hair removal and lesions. Additionally, these mice excessively groom normal cagemates. We have been unable to detect any skin or PNS...

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PMID: 11779477
DOI: 10.1016/s0896-6273(01)00564-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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