Article
Dedifferentiation of adenoid cystic carcinoma: report of a case implicating p53 gene mutation.
Human pathology - 1 Dec 2001
Chau Y, Hongyo T, Aozasa K, Chan J K
Abstract excerpt
Adenoid cystic carcinoma is an indolent tumour with an unfavorable long-term prognosis. Dedifferentiation of adenoid cystic carcinoma, which is associated with an accelerated clinical course, has recently been described. We report a case with immunohistochemical and molecular workup to elucidate the likely mechanism of dedifferentiation. The patient, a 64-year-old woman, developed dedifferentiated adenoid cystic...
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