Article
Characterisation of p-nitrophenylglycerol-resistant Proteus mirabilis super-swarming mutants.
Journal of medical microbiology - 1 Dec 2001
Liaw Shwu-Jen, Lai H-C, Ho S-W, Luh K-T, Wang W-B
Abstract excerpt
p-Nitrophenylglycerol (PNPG) inhibits the co-ordinately regulated activities of swarming behaviour and virulence factor expression in Proteus mirabilis. The inhibitory action of PNPG was investigated by the isolation of Tn5 insertion mutants that could swarm, albeit with much reduced ability, in the presence of PNPG. The mutants exhibited a super-swarming phenotype in the absence of PNPG; i.e., they migrated...
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