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Article

Retardation of cognitive aging by life-long diet restriction: implications for genetic variance.

Neurobiology of aging - 1 Jan 2000

Markowska Alicja L, Savonenko Alena

Abstract excerpt

Long-term moderate dietary restriction (DR) has been reported to extend life spans, delay the onset and decrease the incidence of a broad spectrum of age-associated diseases; however, its effect on cognition is still unclear. Our previous results indicated that long-term DR failed to retard cognitive and psychomotor aging in the inbred strain, Fischer-344 rats. In the present experiment, an anti-aging effect of...

Topics

Aging
Animals
Body Weight
Cognition
Cues
Diet
Discrimination, Psychological
Energy Metabolism
Genetic Variation
Male
Maze Learning
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats, Inbred BN

Rats, Inbred F344

Serial Learning

Species Specificity

Swimming

Source

Identifiers

PMID: 11755022
DOI: 10.1016/s0197-4580(01)00249-4

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